Dr. Apostolakos graduated in 1975 from Aristotle University Medical School.
He received his surgical training at the 401 Military Hospital, Hippokration Hospital and 424 Military Hospital in Northern Greece.
This was followed by a postgraduate fellowship in General Surgery at Kremlin - Bicetre Hospital in Paris, France. During this time, he pursued basic research interests in hepatobiliary surgical procedures under the guidance of Professor M. Testas at Kremlin - Bicetre, Paris.
He also completed a nine month training in hepatobiliary and endocrine surgery under the guidance of Professor P. Larrieu at Antoine Beclere University Hospital in France.